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Uncle Tom's Cabin:
When Uncle Tom's Cabin was published in 1852, it became an international blockbuster, selling more than 300,000 copies in the United States alone in its first year. Progressive for her time, Harriet Beecher Stowe was one of the earliest writers to offer a shockingly realistic depiction of slavery. Her stirring indictment and portrait of human dignity in the most inhumane circumstances enlightened hundreds of thousands by revealing the human costs of slavery, which had until then been cloaked and justified by the racist misperceptions of the time. Langston Hughes called it "a moral battle cry," noting that "the love and warmth and humanity that went into its writing keep it alive a century later," and Tolstoy described it as "flowing from love of God and man." [via]