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Time-series analysis is one of several branches of statistics whose practical importance has increased with the availability of powerful computing tools. Methodology originally developed for specialized applications, for example in business forecasting or geophysical signal processing, is now widely available in general statistical packages. These computing developments have helped to bring the subject closer to the mainstream of applied statistics. This book is an introductory account, written from the perspective of an applied statistician interested in biological applications and throughout analyses of data-sets drawn from the biological and medical sciences are integrated with the methodological development. [via]