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› Find signed collectible books: 'Breakthrough: The Quest to Isolate the Gene for Hereditary Breast Cancer'
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› Find signed collectible books: 'Breakthrough: The Quest to Isolate the Gene for Hereditary Breast Cancer'
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› Find signed collectible books: 'Breakthrough: The Race to Find the Breast Cancer Gene'
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› Find signed collectible books: 'Comp.'
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› Find signed collectible books: 'Cracking the Genome'
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› Find signed collectible books: 'Cracking the Genome: Inside the Race to Unlock Human DNA'
What makes science happen? The confluence of politics, commerce, and the age-old quest for knowledge is nowhere better seen than in the ongoing Human Genome Project. Kevin Davies, founding editor of Nature Genetics, picks apart the personalities and technologies involved in the great sequence race in Cracking the Genome: Inside the Race to Unlock Human DNA. Written not long after President Clinton's premature announcement in 2000 of the Project's completion, it assesses the state of public and private genomic knowledge during what Davies calls "halftime." He is in a unique observational position; as a prominent scientific journalist, he has had unparalleled access to the scientific figures involved. Through interviews with HGP director Francis Collins, rogue scientist-entrepreneur J. Craig Venter, and many other scientists and insiders, Davies illuminates the often-tortured processes that contributed to the speedy sequencing of most--but not quite all--of our genes in just a few short years. Shifting styles characterize the different storylines: technological, political, and intensely personal tales unite under the author's direction without ever alienating the reader. The book is a bit softer on Venter than many scientists (who may perceive him as traitorous or, worse, too hasty to publish) would like, taking the position that his shotgun approach and competitive spirit improved the project without sacrificing quality. Conversely, Davies sits out the gene-patenting controversy, offering all sides a fairly equal voice, but never quite finding sympathy with any of them. Summing up his subject, Davies reports:
If the double helix is the prevailing image of the twentieth century, just as the steam engine signified the nineteenth century, then the sequence--the vast expanse of 3 billion As, Cs, Gs, and Ts--is destined to define the century to come.... The childhood of the human race is about to come to an end.
These are strong words, but few other fields provide a stronger basis for such hope. Cracking the Genome gives us the chance to catch up with the present while the future races on. --Rob Lightner [via]
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› Find signed collectible books: 'Modern Medicine for the MRCP'
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› Find signed collectible books: 'Pause Button'
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› Find signed collectible books: 'Plant Pigments And Their Manipulation'
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› Find signed collectible books: 'Plastids'
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› Find signed collectible books: 'Sequence: Inside the Race for the Human Genome'
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› Find signed collectible books: 'A Tall, Serious Girl: Selected Poems, 1957-2000'
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› Find signed collectible books: 'La Conquista Del Genoma Humano/ Cracking the Genome: inside the race to unlock human DNA'
En 1953, James Watson y Francis Crick descubrieron la estructura de la doble hélice del ADN. Este descubrimiento, que les valió el premio Nobel, constituyó un momento capital en la historia de la genética, pero no permitió descifrar los mensajes que contienen esas cadenas en espiral que se encuentran en el interior de nuestras células. Nadie sabía cuál era exactamente la secuencia del genoma humano. Nadie había descifrado el código de la vida. Ahora, al empezar el nuevo milenio, este código ha sido descifrado. Kevin Davies, director y fundador de la revista Nature Genetics, ha seguido el desarrollo de esta aventura paso a paso, semana a semana, durante diez años. Y ahora nos presenta --por primera vez y con toda riqueza de detalles humanos, científicos y económicos-- el espectacular relato de uno de los mayores logros de la historia de la ciencia: el mapa del genoma humano. Davies ha sabido expresar toda la fascinación de este logro memorable basándose en supropia experiencia en el campo de la genética y en entrevistas realizadas a los principales científicos implicados en la cuestión. También ha visitado a genetistas de todo el mundo para ilustrar convenientemente esta inmensa iniciativa a escala internacional en las fronteras del conocimiento humano. Y así el libro termina siendo una crónica insuperable de la obtención del código que contiene todas las respuestas necesarias para conocer el origen de la vida, la evolución de la humanidad y el futuro de la medicina. [via]
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› Find signed collectible books: 'Comp'
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