Integrating key concepts from biology, medicine, neuroscience, and psychology, Ernest Rossi has forged a revolutionary new paradigm that encompasses mind, body, and spirit. Rossi's new world view-- Psychosocial and Cultural Genomics -- has profound implications for understanding the human condition. He describes how we can all learn to facilitate our evolving consciousness with numinous experiences of Art, Beauty, Truth, and Happiness in our daily creative work of building a better brain. Rossi begins by tracing his own recent dramatic journey from stroke victim through rehabilitation to full recovery. On this journey of self-healing, where he was both passenger and guide, Rossi's full psychotherapeutic repertoire was called upon to facilitate activity-dependent gene expression and brain plasticity to optimize his recovery. As he notes in the closing sentence of this opening chapter: "This takes us quite beyond my personal story to a deepening exploration of the co-creation between consciousness and nature in human experience that is the main subject of this book." As a pioneer in clinical psychobiology, Dr. Rossi shares his latest neuroscience concepts of a unified approach to Mind-Body Medicine and the practical methods self-healing in everyday life.